sábado, 5 de abril de 2014

From an open sewer to a jewel of the city: Aziza Chaouni on uncovering and restoring the Fez River

 

Blog_FF_AzizaChaouni

For much of the past 20 years, architect and engineer Aziza Chaouni has been battling to restore the Fez River, which winds through the city’s medina – Fez’s historic medieval center and a UNESCO World Heritage Site. Heavily contaminated and covered over with concrete to contain the smell, the Fez River had been all but forgotten in recent decades. Not anymore: Chaouni has succeeded in uncovering the river, by working with the city’s water department since 2007, and she is now restoring and reconnecting the riverbanks with the rest of the city, while creating open, green public spaces, allowing the medina to breathe again. At TED2014, we asked her to tell the story of this extraordinary task.

How did you begin the task of uncovering the Fez River?

The whole story actually started as my thesis at Harvard. My thesis advisor told me to do something “that you feel passionate about and that could make a difference.” For years, I’d seen the river in my hometown being desecrated, polluted and filled up with trash and rats. It had become an open sewer and a massive trash yard at the core of the city.

The Fez medina has about 250,000 inhabitants, and all their untreated sewage went straight into the narrow river that runs through it. The river was also heavily contaminated by nearby crafts workshops and tanneries — with chemicals such as chromium 3, which is lethal. People working in the tanneries were getting skin cancer, and some of them were dying. It was terrible. Obviously the river started to stink, so people started building walls to block the view. Then, because it became a health hazard, they covered it with concrete starting in 2002. And because it was covered, people began using that open space as trash yard.

Actually, the first covering began in 1952, when Morocco was still a French protectorate, but it was for political reasons — so that French colonial power could easily enter the medina and control the population. Then, as the population grew and Morocco became independent, covering happened because of the stench.

In your Fellows talk at TED2014, you showed how the water feeds into both public fountains and those in private courtyards. Do people actually use that water? Were they getting sick?

Of course they were, especially from the toxic chemicals dumped in the river by craftsmen. It became dangerous to drink from a running fountain. Besides, a series of droughts and excessive extraction from the water table left little water available for the medina water network. By the 1980s, most of the fountains had become defunct, yet they had been central to its urban fabric. Imagine if Rome had no more running fountains! Can you imagine La Seine or the Thames being suddenly covered? The Fez River is smaller in scale, but the effect is similar: a central part of the city was amputated. When I witnessed all this, I was in college at Columbia University in New York at the time. I would have been 19. I was outraged; I wrote an article in the newspaper and I received hate mail, because of course it made the city look bad. At the time, I was an aspiring engineer. But due to my age and lack of experience, I was not taken seriously.

Pollution in the Fez river. Photo: Aziza Chaouni

Pollution in the Fez River. Photo: Aziza Chaouni

Contaminated water will also have been entering your food supply, your groundwater.

Of course! Yes! Yes and yes and repeatedly yes. It would pollute the water table, which feeds the most fertile agricultural basin of Morocco. But this didn’t upset anyone. Environmental protection is almost seen as a luxury in developing countries: economic development, health and education are understandably bigger priorities. It’s a different mentality in Morocco. I heard many times: “Look, we’re eating the food and we’re fine, hence  nothing’s wrong!”

Many people are eating food exported from Morocco.

I know. And of course it’s not just Morocco — in so many emerging countries, you have high levels of environmental pollution, but you just don’t know about it as there is not much control or accountability. But the point is that if you uncover such a large-scale environmental hazard, even as an architect, you feel outraged and want to do something about it. So I decided, for my thesis, to propose re-envisioning the medina if the river were to be cleaned and uncovered.

My thesis took a slightly different approach to what I’m doing now. You see, the medina of Fez used to boast one of the oldest universities in North Africa, the Quarawiyine, but after Morocco’s independence in 1956, the government established an American style campus outside the city, which symbolized modernity. The university’s move caused the entire cultural life of the city to fade away. In my thesis, I proposed building a university in the medina, with the various departments to occupy the urban voids along the river. These voids had been created when the river was covered: houses were destroyed to make way for the heavy machinery required. My vision was that, once uncovered, the river would serve as a pleasant green feature, and its banks would be used as a circulation system linking the departments. Classrooms would be located in nearby abandoned buildings. The university model was unusual and innovative: it would be one of a heterogeneous network of buildings embedded within the medina’s urban fabric.

For me, bringing back the water and the university represented a double win. The university idea hasn’t happened yet, but working on this thesis allowed me to start thinking about the potential of the river for the city and its inhabitants. Many ideas I developed back then became a solid departure point for the actual project, which I started in 2007 in collaboration with my then-partner Takako Tajima.

You’d been thinking about uncovering the Fez River for almost 10 years by then. How did the Fez River Project become a reality?

When Takako and I learned in 2007 that the city would finally be diverting and treating the medina’s sewage, we knew that with clean water, it would be possible to uncover the river and use its banks. We could create much-needed green, open space in the medina. It only has 43.5 square feet of green space per person, while UN standards recommend between 215 to 275 square feet per person.

Inside the medina, the uncovering of the river opened up new possibilities to restore the river banks as pedestrian pathways, reconnect the river banks to the city fabric and transform what used to be urban voids into green, open spaces. So we proposed three main interventions: a pedestrian plaza, a playground and a botanical garden. We used four main strategies: precisely placed interventions strategically phased to enhance water quality, remediate contaminated sites, create open spaces, and build on existing resources for economic development. These interventions had to benefit the population on several levels — social, environmental, economic, urban — and be resilient, so that it would still function regardless of changes in budget, political climate, and so on.

At the wider city scale, we needed to prevent the newly cleaned river water inside the medina from getting polluted upstream, so we recommended measures for improving regional water quality, too. Depending on soil geomorphology, levels of water pollution, adjacent urban fabric and ecological systems, we purposefully located various rehabilitation tactics like canal restorers, constructed wetlands, bank restoration and storm-water retention ponds.

Before: A portion of the Fez river before uncovering, the concrete plaza being used as a dump. The blue marks indicate the locaation of the river. Image: Aziza Chaouni

Before: A portion of the Fez River before its uncovering. The concrete plaza being used as a dump and the blue marks indicate the location of the river. Image: Aziza Chaouni

Now that the water is clean, is biodiversity coming back?

Not inside the medina, but downstream. The changes in biodiversity are definitely noticeable: the flora looks more healthy. Inside the medina, there’s now construction, and craftsmen have not completely stopped polluting some areas of the river and its banks. So it’s more of a long-term goal, but it will happen.

It sounds as though you met with a huge amount of resistance. Yet now, the Fez River Project is celebrated. How did this happen?

The moment things changed was when we won two very important design prizes, called the Holcim Award for Sustainability in 2007. It’s one of the most lucrative prizes — up to $400,000 for the Gold Regional and Global awards — in the design field. The prize brought the Fez River, its problems and potentials to the attention of a large public. When something becomes that important publicly, there are many new stakeholders that emerge — everyone wants to help the project while projecting their own agendas. Suddenly, many voices started to be heard. But sadly, our input was seen as less necessary or relevant. So it became something of a battle.

Why is having many people interested difficult?

Having many voices interested in architectural and urban issues is a positive thing in many regards: for example, it can allow for a democratic design process. However, it can sometimes also create hurdles and harm a project as it dilutes its central design ideas. As some of my colleagues have observed, any municipal project around the world is the most complex project you can possibly work on, especially on a large scale. Because there are just so many variables, there are so many changes in the sociopolitical landscape, and so many commercial and economic interests colliding.

After: What this portion of the river will look like once it is uncovered, and the area shaded built to create a public plaza. Image: Aziza Chaouni

After: What this portion of the river above will look like once it is uncovered, and the area shaded built to create a public plaza. Image: Aziza Chaouni

But fortunately, there is no turning back now. The river is uncovered — a process that took three full years — and the first public space is almost finished. It’s a plaza. People are using it, even though it is still under construction. So, no matter what the design ends up looking like or how people change it, at least the worst has been avoided: the river could have remained terribly polluted and its existence even forgotten by the inhabitants of the medina, erasing a large part of the history of the city. Like in other other medinas in the Middle East, the covered river could have easily become a vehicular road, which is a harbinger of bad news for medinas.

When roads are introduced into these medieval cities, their pervasive pedestrian network starts to slowly be transformed. Narrow pedestrian streets become larger and are gradually replaced by roads. Also, once-inward-facing houses start to open up with businesses facing towards these new, large roads. As a result, the medinas’ urban fabric loses its unique character, which is marked by an organic, labyrinthine pedestrian system. The medinas of Tunis and Algiers illustrate well this tragic, irreversible transformation.

How many more years before your final vision comes to pass?

For me, on a fundamental level, I would say that the core of our vision has happened: the river has been resuscitated, both figuratively and literally. It is uncovered and acknowledged by all as a “river,” not a sewer. This presents a unique potential for the medina of Fez. A key lesson we have learned is that a resilient design project, with a solid core idea, can surmount any changes that come its way. Its core idea will remain, even though its aesthetics, timeline, methodology will drastically changed. In architecture school, we are taught that one’s project should be implemented as closely to one’s drawings as possible. In developing-world contexts, especially while working on municipal projects, this task is almost impossible. The architect needs to leave his or her ego in the back seat and develop a resilient, phased design with key principles that can sustain changes of stakeholders in the socio-political sphere, with the economic landscape and so on.

How much are you invested personally in the Fez medina? Did you grow up here?

My dad and my grandparents on both sides of the family were born and raised in this medieval city, so it’s absolutely very close to my heart. I grew up not inside the medina, but in the newer part of the city, right next to it. What’s amazing is that it’s not a place for tourists — it is a living city, and not much of its urban fabric has changed since the 7th century. People live there, work there — so if you want to buy, for example, a type of cake, special fabric, sweets or pickles, it can only be sold in certain neighborhoods of the medina. Tourists do go there as well, of course, but the medina of Fez has not given way to massive gentrification.

It sounds magical.

When my American mother-in-law, who’s a historian, came to Fez, she said, “I never felt so much that I was back in time, back in the medieval era. You almost forget which time period you’re in.”

You call yourself a nomad, and work on quite a few other projects around the world, specializing in eco-tourism in arid regions. But your work in Fez must take up a huge amount of time.

Let’s say I am a semi-nomad with a double life. I am an assistant professor at the University of Toronto, and I have a small design office with two people in Toronto, and an office of five people in Fez, my hometown. I usually spend about three months of the year in Fez, and I keep daily contact with my team and clients while I am in Toronto.

The nice thing about the University of Toronto is that it’s a research university, so I am expected to work on research projects. Obviously, I like to link my research to my practice, as they both feed on each other. I’m not an architectural historian — I teach students to become professional architects, so it is a big asset to be practicing, especially in countries like Morocco. That way, I can share with my students design expertise specific to developing world contexts.

I also have an applied research lab called DET at the University of Toronto that focuses specifically on ecotourism in emergent countries, in very remote areas. I have been focusing on deserts and arid climates these past years, and I have worked on projects in Southern Morocco and Jordan.

Proposed dwelling sites for an eco-tourist destination in Ain Nsissa nature reserve, Morocco. Image: Aziza Chaouni

Proposed dwelling sites for an eco-tourist destination in Ain Nsissa nature reserve, Morocco. Image: Aziza Chaouni

Can you give us an example?

Well, we work with the Moroccan Ministry of Tourism, for example, when they need to set up guidelines for investors to develop tourism projects in fragile, remote sites. Of course, Morocco is a developing country, and they want outside investors, but they also know that if they just let people do whatever they want, they will mess up those landscapes. In a desert, there is no margin for error. You mess it up, you kill everything, and that’s it. You’re all done. You have so few resources, too. So investors can be scared to come in.

With the help of my mentor and thesis advisor, Professor Hashim Sarkis, I was able to convince the Moroccan Ministry of Tourism to finance my students’ trips to Morocco. Then, under my guidance, they develop innovative solutions and guidelines, which then become bylaws. We started developing, for example, new types of ecological nomadic tents that leave very little impact on their context—they fold up and can be moved easily.

Then, I was asked to work in Jordan by the Royal Society of Conservation of Nature (RSCN), also in a desert area, to help them establish a new protected area north of Petra called Shobak. RSCN, an NGO, runs all national parks, not the government. Since they only receive 10% of their money from the government, they need to generate the other 90% to conserve nature. So they rely on eco-tourism, and wanted new ideas about how to develop it. The fact that I speak Arabic, and that I can also easily speak to women because of my gender, has been a big asset to understand the aspirations of local populations. A lot of men from these remote areas migrate to cities, so mostly women are left.

And you’re working on a Canadian project, as well?

Yes, after I’d been to Jordan, I collaborated with Parks Canada in Toronto to study the first very urban national park in Canada, Rouge National Urban Park, created in 2012. I applied for a grant to compare Rouge Park, which is right in the middle of the suburbs, with another urban national park in Rio, Guaratiba Biological Reserve, which contains a unique mangrove habitat. Both parks are adjacent to large, sprawling cities, and they will be under even more pressure in the future. How can we manage parks like this in new ways? How can we build next to these new parks?

Thanks to a LACREG grant, we did research for two years, then created an app that compares the two parks — how they are run and funded, their adjacent urban areas, their leisure activities, their ecosystems, endangered species. But the part we’re most proud of is that we created guided tours with a feature that allows visitors to become stewards of the park by reporting environmental abuse. Because these parks are usually not well-known, people can take different tours that will explain their history. But the most important issue is that urban parks are very hard to manage because they are readily accessible, and park rangers have a hard time being vigilant. So the app allows anyone who sees something or someone harming the parks — such as littering, poaching, off-leash dogs, harming wildlife — to take an image, immediately upload it to Flickr, and geo-tag it.

 

From sewer to jewel- Aziza Chaouni on uncovering the Fez river - TED Blog 2014-04-05 05-27-12

Coming to Your Twitter Feed: 15 New Types of Ads

 

April 4, 2014 2:31 p.m. ET

New ads—lots of new ads—are on their way to Twitter Inc. TWTR -2.07%

Hoping to win over e-commerce companies and mobile-game developers, the communications platform will debut 15 types of new ad products and improved ways to target users over the next six months, according to people familiar with the company's plans.

The first batch will be released in a few weeks and will include a product that will coax users to download apps through Twitter, these people said.

Over the past year, some consumer brands have thrown more advertising dollars toward Twitter, especially during live events such as the Super Bowl or Academy Awards. Twitter's simple suite of promoted advertising products—a trio of ads that target select users and receive preferential placements as tweets, trends and recommended accounts—haven't resonated with mobile game and e-commerce companies whose advertising decisions are driven by app downloads, subscriber sign-ups and purchases.

Twitter's advertising revenue, which makes up the bulk of its earnings, more than doubled in the fourth quarter to $219.6 million from the same period a year earlier. Twitter, which has yet to turn a profit, is under pressure to show its young advertising business is deserving of its current market cap of $26.9 billion. The company's stock has fallen about 33% so far this year to $42.96, approaching its post-IPO low of $39.06.

A Twitter spokesman declined to comment.

To address advertisers' needs, Twitter is taking a page from Facebook Inc. FB -4.61% 's playbook. Twitter has been beta-testing a mobile-app install ad unit. It is similar to the popular product Facebook launched in late 2012 and that has fueled its mobile advertising revenue, which last quarter accounted for more than half of overall revenue for the first time.

Facebook users downloaded 245 million mobile apps after seeing ads for those apps in their news feeds last year. It essentially recommends apps for Facebook users to download. Replete with an "install now" or "shop now" button, the format has been used by mobile game companies such as London-based Supersolid, the developer behind "Super Penguins" and "Adventure Town."

"Not having the direct-app install link is an issue," said Edward Chin, a Supersolid co-founder about why the company has yet to advertise on Twitter. Instead, "a lot" of Supersolid's advertising budget is spent on Facebook.

The app-install ad unit will be delivered using Twitter's "card" technology, an expandable tweet allowing advertisers to include a button that lets users perform the desired action. When users click a "download" button, they are taken to Apple Inc. AAPL -1.29% 's app store where they can download the app. Once it starts downloading, the user is automatically taken back to the Twitter app. This format brings Twitter more in line with app-install ads on Facebook.

Twitter has been experimenting with other ways to use the card to boost users' engagement with advertisers. For example, it tested a "call-to-click" button that would put users on the phone with businesses. The company has also been in talks with payments processor Stripe Inc. to help allow users to purchase goods directly through Twitter.

Twitter's top executives, including CEO Dick Costolo, showed off a sampling of these new ad offerings to a troop of visiting ad industry executives last week, according to a person who attended the meeting. Whereas Twitter Cards is currently limited to seven predetermined formats, executives suggested the product will become a more open platform that would give marketers more creative freedom to come up with their own uses of Cards. Twitter, for example, showed how Cards can be used to encourage users to sign up for sweepstakes and contests with one-click sharing of their email addresses.

As Twitter ushers out more ad products, the company will need to be careful not to inundate users with too many ads. Twitter has long maintained that the user experience comes first—one where the main timeline isn't overwhelmed by a rush of ads. The amount of ads served in users' timelines haven't increased much since 2010 when Twitter debuted its first advertising product.

Twitter will also need to find a way to bring down the customer acquisition costs through its ads. AdParlor, a social-media advertising manager, estimates the cost of acquiring a new user through Facebook is below $4 in the U.S. That compares with a current cost of about $20 through ads on Twitter, according to a person familiar with the matter. Recent beta-test results of the app-install unit show that the cost has become more competitive with Facebook, this person said.

Japanese mobile gaming company Gree Inc. 3632.TO -1.41% said Facebook's mobile app install ad unit is one of the top three drivers of its game downloads. Sho Masuda, Gree's vice president of marketing, said the combination of factors such as scale, having a clear call-to-action button, visually-driven ad format and refined targeting capabilities make the Facebook ads effective.

"We have made attempts trying to make it work but have not seen the scale we want," said Mr. Masuda of the company's experience advertising on Twitter. "We're providing feedback [to Twitter] on how else we can shape their product in a way that works for us," Mr. Masuda said. He declined to comment on whether Gree was testing any ads, though an ad urging users to download its "Knights and Dragons" game has been seen on Twitter.

Other app-install ads that have recently shown up in users' streams include those from mobile-payments company Square Inc. Digital-music streaming service Spotify AB is one of Twitter's beta testers, according to a person familiar with the matter. Stockholm-based Spotify declined to comment.

Beyond advertising, Twitter has also begun improving methods of targeting users by offering a wealthier trove of data in recent months, a move that follows Facebook's footsteps. In December, Twitter signed or expanded partnerships with large third-party data marketers such as Datalogix Inc. and Acxiom Corp. ACXM -6.05% that allow advertisers to target users based on their consumer behavior when they are not on Twitter. While the two databases can't make out personal identifiable information such as email addresses and phone numbers, combining the databases can inform advertisers what Twitter users are doing when they are away from the service.

More detailed knowledge of Twitter's user segments could convince game developers like Mr. Chin of Supersolid to give advertising on the real-time service a chance.

Mr. Chin said Facebook's wealth of user data also allows for more "quality downloads" where the sophisticated targeting capabilities make it more likely that users continue to play the game after downloading the app.

—Hannah Karp contributed to this article.

Coming to Your Twitter Feed- 15 New Types of Ads - WSJ.com 2014-04-05 05-03-37

Body vive active : enfin une activité pour les "larguées" des cours de fitness

 

Par Emilie Cailleau | Topsante – jeu. 27 mars 2014

Trop rapide, trop compliqué. Si vous avez toujours l'impression d'être la mauvaise élève à votre séance de gym, ce nouveau cours Les Mills devrait vous plaire. Présentation en exclusivité.

Redonner goût au sport

A la gym, vous préférez attendre contre le mur que le cours se passe ? Plutôt que de transpirer par procuration, essayez donc le Body vive active. Présenté au Salon Body Fitness, ce nouvel entraînement de la planète des Mills veut remotiver les troupes. Celles qui ont abandonné leurs résolutions sportives, les novices et les déçues des clubs.

Du fitness à son rythme

Quelle différence avec un cours de fitness classique ? L'activité est plus accessible. On n'est pas larguées si on se trompe de pied ! Les chorégraphies sont faciles à suivre et on adapte l'intensité des mouvements. "C'est le plus complet du programme des Mills, explique Laurence Klares, directrice du training les Mills Euromed. On élève la fréquence cardiaque avec des pics d'intensité et on renforce les muscles avec des exercices basés sur un "tubing", une sorte de tube élastique qui augmente la résistance".

Autre argument de taille pour celles qui s'ennuient vite : les séances sont proposées au choix dans un format de 30, 45 ou 55 minutes. Pour un cours de 55 minutes, on alterne 25 minutes de cardio et 25 minutes de renforcement musculaire avec le tubing. Pour les formats plus courts, l'effort est mis sur le cardio, en vertu du principe d'"aérobie" : le muscle puise dans les graisses pour fonctionner. Du coup on perd du poids plus vite (on perd 550 calories par cours de 55 minutes en moyenne).

Concrètement ça donne quoi ?

On retrouve les gestes du Body attack, sans être trempée comme à la sortie d'un hammam. On respire mieux et on prend du plaisir à effectuer les mouvements : déplacements latéraux, sauts, course, squats, fentes, talons-fesses, etc.

On le pratique où ?

Présenté en avant-première à Paris, l’activité devrait débarquer dans les prochains mois dans les centres dispensant des cours Les Mills. Trouvez les clubs concernés près de chez vous sur le site www.fitness.fr.

>> Plus de conseils forme sur (...) Lire la suite sur Topsanté

Salon Body Fitness, c'est parti!
Ski : bien coachée pour les sports d'hiver
5 bonnes raisons de faire du sport en hiver
2h30 de sport par semaine réduirait le risque de grippe
Forme : Born to move, du fitness amusant pour les enfants

 

Body vive active - enfin une activité pour les -larguées- des cours de fitness - Yahoo Actualités France 2014-04-05 04-54-55

Les médecins vont bientôt tester la prescription au « retour à l'activité physique »

 

 

Des discussions entre le ministère de la Santé, le groupe de fitness Vit'Halles et les médecins du 15ème arrondissement de Paris sont actuellement en cours pour lancer une opération pilote consistant à prescrire « un retour à l'activité physique par des protocoles de 8 à 12 semaines ». Alain Barasz, Directeur Général du groupe Vit'Halles, a confié que l'expérience pourrait démarrer en avril prochain.

Les médecins vont bientôt tester la prescription au « retour à l'activité physique » - Crédit photo : © grafica Cette opération pilote consiste à prescrire des "modules de 8 à 12 semaines" à réaliser dans le centre Vit'Halles du 15ème arrondissement de Paris. Les personnes diabétiques, qui connaissent des problèmes d'obésité, ou d'autres soucis de santé sont concernées par l'expérience. Les séances de sport seront ainsi adaptées à la condition physique de chaque patient.

"A l'avenir, tous les médecins pourrait prescrire l'activité physique. L'idée de cette opération, que l'on va baptiser "Retour à l'activité physique", est d'inciter aussi les gens à continuer à faire du sport, même lorsque leur protocole arrive à terme", explique Alain Barasz, Président de la Fédération Nationale du Fitness et du Footing Associé.

L'opération se déroulera dans le 15ème arrondissement de la capitale car "il s'agit du secteur le plus peuplé. Plus de 300.000 personnes y vivent et 175 médecins y exercent", précise le professionnel.

Pour l'heure, la première étape vers "le retour à l'activité physique" consiste à conclure des accords avec les mutuelles de santé pour permettre aux abonnés d'être pris en charge. Swiss Life est le premier organisme à travailler avec le groupe Vit'Halles. Ses assurés peuvent ainsi bénéficier d'une prise en charge de leur abonnement dans les clubs de sport du groupe à hauteur de 100 euros, peu importe la formule de couverture choisie. L'abonnement annuel coûte en moyenne 600 euros dans les centres Vit'Halles.

"Ce n'est que le début. Swiss Life ne devrait pas être le seul à participer à ce nouveau mode de fonctionnement. Nous souhaiterions ouvrir une brèche et inciter les autres mutuelles à nous rejoindre". Il s'agit de leur dire ''en prenant en charge l'activité physique de vos assurés, ces derniers tomberont moins malades. Vous ne pouvez qu'être gagnant", prévient le Directeur Général du groupe Vit'Halles.

Le professionnel travaille actuellement à la création d'un label des clubs de fitness pour inciter justement les mutuelles de santé à rejoindre ce programme. Seuls les centres mettant en oeuvre un "programme sérieux" pourront bénéficier de ce label en 2010.

Actuellement, il existe 2.500 clubs de fitness en France. Quelque 30.000 Français s'entraînent dans l'un des dix clubs Vit'Halles. "Seuls 5% de la population française est inscrite dans les salles de fitness contre 15 à 17% de la population anglaise, hollandaise, italienne ou belge", rapporte Alain Barasz.

Outre le fait d'être peu nombreux, les Français se distinguent également par un taux d'abandon élevé. 35% des nouveaux abonnés ne se dépensent plus dans les salles où ils se sont inscrits au-delà de la sixième semaine. "En général, ces nouveaux sportifs ont commencé avec des cours trop difficiles. Ils ont eu des courbatures et n'ont eu aucun résultat, ce qui ne leur a pas donné envie de revenir. Les résultats se font pourtant ressentir à partir de la huitième semaine, en venant au moins une fois par semaine" confie le professionnel.

A noter que 60 à 65% des abonnés en France sont des femmes, qui pratiquent une fois par semaine, généralement entre 12h et 14h.

Source : © NUTRINEWS



Publié par Alexandre Glouchkoff, diététicien nutritionniste. Lien d'intérêt : Aucun

 

Les médecins vont bientôt tester la prescription au « retour à l'activité physique » 2014-04-05 04-48-11

Live Longer with This 30-Minute Habit

 

th

You could cut your mortality risk dramatically if you just did this for 30 minutes: walk.

Or ride your stationary bike. Or dance. Or chase the grandkids around outside. Or shovel some snow. Or all of the above. Just be active for 30 minutes, five times a week. This simple choice cut mortality risk by nearly 20 percent in a recent study.

Walk the Walk
You can't be your best and be there for others unless you take care of yourself first. So no matter how busy life gets, make time for the active things in life that you enjoy. Doesn't have to be a killer ab workout or a sweat-till-you-drop spin class. In a study, people who simply did nonvigorous physical activity for 2 1/2 hours a week saw their risk of dying from any cause drop by almost 20 percent compared with the couch potatoes. If there's no special activity that floats your boat, just walk. Hoofing it for 30 minutes, five times a week, is a small and easy investment to make in your long-term health.

 (What can walking do for you? Check out this Top 10 list.)

Moving Matters
Of course, a little sweat is healthy, too, so if you want to crank it up a notch, and you don't have any health conditions in the way, feel free. When the people in the study kicked activity levels into high gear -- logging 7 hours of moderate-intensity exercise each week -- their mortality risk dropped by 25 percent compared with nonactive folks. Chalk it up to the favorable impact exercise has on weight (active people gain less over time) and blood pressure (exercise helps keep those blood vessel walls nice and relaxed). Make walking a regular part of your life with these easy strategies:

Learn the four secrets to turning your walk into a serious weight loss tool.

 

RealAge Benefits

A physical activity program that builds stamina, strength, and flexibility can make your RealAge as much as 2.8 years younger. Take the RealAge Test!

 

Live Longer - Walking 30 Minutes a Day - Health Tip - Sharecare 2014-04-05 04-34-53

sexta-feira, 4 de abril de 2014

Wear Luck Uses Clothing To Promote Positivity And Self-Improvement

 

April 4, 2014 3:31 pm by: Clarissa Burt - Category: Fashion News

“It’s clothing with a purpose.”

That is the goal of Wear Luck, the clothing line aimed toward influencing a positive state of mind, good luck and self-improvement. The company has six shops within itself: Wear Luv, Wear Yoga, Wear Hope, Wear Intent, Wear Balance and Wear Fitness. Each shop is designed to provide the wearer with a different inspirational message.

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Each line within the brand has a different creator and each of these creators have the hope of influencing wearers in a positive way.

Wear Luv, by Dallas Cowboys Cheerleaders trainer Lin Johnson, focuses on kindness and anti-bullying with shirts displaying messages such as: “Luv Who You Are,” “Luv Is My Addiction” and “I Luv Us.”

According to Johnson in Wear Luv’s online description, “It truly forces the wearer of the shirt—to have a good attitude!”

At the March 6, 2014 premiere of “Mr. Peabody & Sherman,” actress Blanca Blanco wore the Wear Luv top reading “I Rock” on the front “And So Do You” on the back.

Johnson’s husband and trainer of the Dallas Cowboys Cheerleaders, Jay Johnson, also created a line for Wear Luck called Wear Fitness. The shirt “Sweat is Sexy” is meant to motivate the wearer to push their limits during workouts.

Author Lissa Coffey created Wear Yoga. The line focuses on using colors and symbols that help the wearer reach their “dharma,” which is a Sanskrit word that means “purpose.” Coffey explains in her book “What’s Your Dharma?” that there are four paths that can lead to this self-discovery and her line encourages those paths.

A mother of two special needs children is behind Wear Hope for Wear Luck. She uses her story and line to encourage wearers that they can endure any challenges placed in front of them.

Wear Intent was created by Mallika Chopra, who founded an online community targeted toward encouraging people to make their aspirations a reality with the power of intentions. Her line reminds wearers to be mindful of their intent.

Feng Shui entrepreneur Kathryn Weber uses Wear Balance to help the wearer bring what is out of balance in their lives into focus. With shirts dedicated to prosperity, fame, romance, family, health, creativity, wisdom, career and confidence, each has a unique color and message.

With its expansion into these positive lines, Wear Luck is gaining popularity and recognition, and they are definitely a brand to watch out for in 2014.

 

Wear Luck Uses Clothing To Promote Positivity And Self-Improvement - Los Angeles Fashion - The LA Fashion magazine 2014-04-04 20-22-29

El Economista de Cuba- Ciencia, tecnología y economía mundial

 

Ciencia, tecnología y economía mundial: persistencia de asimetrías y emergencia de nuevos actores
Por Guillermo L. Andrés Alpízar - Rebelión

Aunque en el contexto de la crisis global se asiste a un afianzamiento de los cambios globales que en cifras gruesas determinan un mejor posicionamiento de las economías del Sur, estas transformaciones ocurren de forma muy desigual, afianzando el desarrollo asimétrico de la ciencia y la tecnología por todo el orbe

[04-04.2014]- Actualización 9:00 am de Cuba
Una mirada a la evolución más reciente de los principales indicadores de ciencia y tecnología a nivel global, apunta a una reducción de la comúnmente denominada "brecha" que separa a los países del Norte de los países periféricos. Al respecto las estadísticas de la UNESCO aseveran que si en 2002 los países subdesarrollados ejecutaban el 17,5% del gasto mundial en investigación y desarrollo (I+D) y poseían el 30,6% de los científicos del mundo, siete años más tarde invirtieron el 27,1% y dispusieron del 36% del total de los investigadores (UNESCO, 2013). Sin embargo, ¿Quiere decir ello que se asiste a un despegue real de la ciencia en el Sur? En estos cambios, ¿qué rol desempeñan las economías emergentes y en particular, China?

Para responder a estas preguntas resulta necesario comenzar analizando la evolución de las inversiones globales en ciencia y tecnología durante los últimos años, donde se muestra un incremento sostenido en los volúmenes de financiamiento, los cuales a pesar de ligeras desviaciones han acompañado el crecimiento de la economía mundial. En 1992 los gastos mundiales en investigación y desarrollo ascendieron a 428,5 mil millones de dólares (estos datos se ofrecen en dólares de Estados Unidos, en paridad de poder adquisitivo). Quince años más tarde, ese monto se elevó a 1,16 billones de dólares y para 2009 -el último año disponible con una cuantificación del total mundial- estos fueron 1,28 billones. El incremento en los volúmenes de financiamiento, implicó una ligera disminución en la intensidad global de las inversiones en ciencia y tecnología, pues si en 1992 el total del Gasto Bruto en Investigación y Desarrollo (GBID,) representó el 1,8% del PIB mundial, en 2009 su participación fue del 1,77% (UNESCO, 1996) (UNESCO, 2010) (UNESCO 2013).

Este último año, los países desarrollados, donde reside el aproximadamente el 20% de la población mundial, ejecutaron el 72,9% del total de gasto en I+D, mientras que en los países subdesarrollados, con el 80% de la población restante, esa participación se limitó al 27,1% del GBID mundial. Como promedio, los países subdesarrollados destinaron a las actividades de investigación y desarrollo el 1,11% de su PIB (en el caso de los Países Menos Avanzados fue el 0,2%) mientras que los países desarrollados la media fue del 2,32% (UNESCO, 2010) (UNESCO, 2013).

Al examinar la distribución asimétrica de los gastos en I+D, pueden identificarse otros niveles de estratificación, entre las diferentes regiones o países. Estos contrastes se ponen de relieve con especial énfasis dentro del conjunto de países subdesarrollados. Por ejemplo, en América Latina, Brasil ejecuta el 70% del gasto regional en I+D, y junto a México y Chile esa proporción se eleva al 90%, por lo que los treinta países restantes solo ejecutan el 10%. En el continente africano, Sudáfrica concentra el 40% del exiguo GBID, mientras que al resto de los países subsaharianos realizan el 28,8%. En Asia el 78% del GBID -excluyendo a Japón-, aparece en las cuentas de China, Corea del Sur e India. Si en dicho conjunto se incluye a la nación nipona, el porcentaje se eleva al 85% (UNESCO, 2013).

Este reconocimiento de los múltiples niveles de asimetrías, ya sea entre estados o regiones, aunque pueda involucrar a países con similares niveles de desarrollo, no puede pasar por alto que en las asimetrías Norte-Sur, es donde en última instancia radican los principales desafíos para este último grupo, pues ellas revelan y explican las condiciones de dependencia tecnológica en la cual se encuentra la inmensa mayoría de los países subdesarrollados, mientras que aseguran la utilización de la ciencia como un instrumento de dominación por parte de las economías más avanzadas, lo cual es además un factor decisivo para mantener su status quo en la economía mundial.

Sin embargo, aún en contra del mandato de esta lógica, en el informe de la UNESCO 2010 sobre el Estado de la Ciencia en el mundo se alertaba de un cambio en las tendencias observadas históricamente.

Allí se describe el ascenso del Sur en ciencia y tecnología, el cual se ve reflejado a través del desplazamiento de la influencia científica mundial en detrimento de la llamada "Tríada" (Estados Unidos, la Unión Europea y Japón) y en beneficio de una "nueva Tríada" compuesta por Estados Unidos, Europa y Asia (UNESCO, 2010).

La recomposición en el panorama científico mundial (que se muestra con claridad en varios indicadores agregados), a su vez se ha visto acelerada a consecuencia de los efectos de la crisis económica global, en la cual se han afianzado patrones de crecimiento totalmente divergentes, reflejados en altas tasas de incremento del PIB en algunas economías y mientras que se mantiene la recesión o el estancamiento en otras. Desde el punto de vista de las grandes regiones geográficas, mientras que América y Europa disminuyen en varios puntos porcentuales su participación en los gastos globales de I+D, Asia muestra un aumento sostenido y llega en 2009 a representar el 32,2% de esos gastos (UNESCO, 2013).

En las economías asiáticas, la influencia de los cambios liderados por China ha sido muy significativa en diferentes órdenes. Entre 2002 y 2009 este país pasa del 5% al 12,1% de los gastos mundiales en investigación y desarrollo, alcanzando ese último año más de la tercera parte del GBID regional, mientras que el cambio de su peso dentro del conjunto de países subdesarrollados es aún superior, pasando del 28,5% en 2002 al 44,6% en 2009. Estas variaciones significan, además, que el gigante asiático, con una elevación del gasto de 114,9 miles de millones de dólares, aportó el 55% del incremento del financiamiento observado en los países subdesarrollados durante dicho período, y de mantenerse la actual tendencia, resulta evidente que va acercándose el momento en que China realizará la mitad del total de los gastos en I+D de los países del Sur (UNESCO, 2013).

Desde otra perspectiva, los resultados del resto de los miembros del grupo BRICS, han sido, en cierta medida, diferentes. Según la UNESCO, Brasil realiza el 1,9% del gasto mundial en I+D, India el 2,1%, Rusia el 2,6%, y Sudáfrica el 0,4%. En conjunto estos cuatro países, con un aumento de 43,1 miles de millones de dólares, aportaron el 20,8% del crecimiento del gasto de los países subdesarrollados entre 2002 y 2009, un 37,5% del total del crecimiento aportado por China (UNESCO, 2013). Esto refleja que si bien, visto como grupo, las economías BRICS mantienen un peso decisivo en la evolución de las tendencias de la ciencia y la tecnología para el conjunto de países "en desarrollo" al aportar cerca de las tres cuartas partes del incremento de los gastos en ciencia y tecnología, es evidente que las contribuciones de estos cinco países han sido muy diferentes, mostrando un dinamismo variable en cada uno de los casos. Estas contribuciones han ido, desde la presencia inobjetable de China al frente de las transformaciones globales, hasta condiciones de lento crecimiento, puestas de manifiesto en los casos de Brasil y Sudáfrica, las cuales son compartidas por muchos países periféricos.

Las estadísticas globales, por lo tanto, han visto un incremento sustancial del peso del Tercer Mundo en los indicadores globales de ciencia y tecnología que no responde a una evolución sincronizada y coherente en el desarrollo de sus sistemas nacionales de innovación, sino por el contrario obedece a la lógica de una evolución diferenciada que tiene a países comprendidos dentro del mismo grupo en polos opuestos. Por esta causa el mayor peso que apariencia tienen las economías subdesarrolladas en los principales indicadores científico-tecnológicos globales, tiende a enmascarar la dinámica real del desarrollo científico y tecnológico de este conjunto de países, ocultando el estancamiento en el que se encuentran vastas regiones planeta, lo cual es el caso, por ejemplo, de los países africanos, y en especial de los Países Menos Avanzados (PMA). Es preciso recordar que los PMA están compuestos por 49 naciones, la mayoría de ellas ubicadas en el continente africano, y viven allí 798,5 millones de personas, o sea, el 12% de los habitantes del planeta. El gasto en I+D de ese conjunto de países durante 2009 fue de 2,1 miles millones de dólares (a PPA), lo que representa apenas el 0,2% tanto de su PIB como de su participación en las inversiones globales ciencia y tecnología.

Siete años atrás, cuando el gasto fue de 1,3 mil millones, ese porcentaje fue similar (UNESCO, 2010) (UNESCO, 2013) Por otro lado, en el caso de las economías más dinámicas, los incrementos generados en materia de gastos, investigadores o publicaciones, no garantizan que estos se conviertan automáticamente en desarrollo científico-tecnológico e innovaciones con un impacto significativo en la economía, aunque en el largo plazo contribuyan a crear las condiciones para que eso ocurra. Para los países asiáticos emergentes que participan en dichos procesos, tampoco puede soslayarse el efecto de las prácticas de "maquila intelectual" o transnacionalización de la ciencia, que son impulsadas por las empresas multinacionales, y que por lo tanto dificulta la capacidad para determinar hasta qué punto la innovación es endógena y cual es en realidad el resultado de procesos de deslocalización de la producción proveniente desde los países desarrollados, fundamentalmente Estados Unidos y Europa (Delgado, 2011).

En síntesis, aunque en el contexto de la crisis global se asiste a un afianzamiento de los cambios globales que en cifras gruesas determinan un mejor posicionamiento de las economías del Sur, estas transformaciones ocurren de forma muy desigual, afianzando el desarrollo asimétrico de la ciencia y la tecnología por todo el orbe.

Particularmente los países emergentes han desempeñado un rol fundamental en estos procesos, aunque inclusive dentro del grupo BRICS los resultados son muy heterogéneos, destacándose el papel de China como el actor más dinámico e influyente en ese grupo.

 

El Economista de Cuba- Ciencia, tecnología y economía mundial- persistencia de asimetrías y emergencia de nuevos actores 2014-04-04 18-49-34

5 biometric alternatives to the password

 

The Nymi wristband detects a wearer's unique heartbeat and could be used to unlock devices, start cars and open doors.

(CNN) -- There are many things that make you special: Your sense of humor, your dance moves, your personal style, the shape of your ear.

That's right, your ear.

The password has had its moment, but those hard-to-remember strings of number and letters are increasingly insecure and clumsy to manage. The next wave in computer security will be biometric authentication, the futuristic practice of using unique behavioral and biological traits such as fingerprints, gait and yes, even ear shape to confirm your identity.

You might already have the necessary equipment to detect some of these your pocket.

Smartphones are packed with powerful sensors that can be used to make sure you are really, well, you. They have accelerometers, gyros, sensitive touchscreens, microphones and high-resolution cameras, all of which can gather information about physical traits and behaviors that make each person unique.

Fingerprints are the most well-known biometric identifier. Apple took an early stab at this technology by embedding a fingerprint sensor into the home button of its iPhone 5S, with mixed results.

Biometrics are still a long way from replacing the password -- they have kinks that must be ironed out, and making them work with current systems will take some time. There are also serious privacy concerns to consider when it comes to collecting information in databases that would identify people.

But these changes are coming. Here are five biometrics that are part of the next wave of identification technologies.

Heartbeat

Your heart's activity and its electrical signals are distinct and very difficult to replicate. The technology for reading an individual's electrocardiographic signals (ECG) has been around for many years, but recent advancements have shrunk the sensing devices to small sizes and made them less invasive.

Something as common as a wearable fitness device or subtle as a flat pad embedded on to the side of a smartphone can detect a person's heart rate. Apple has even applied for a patent on an embedded heart rate monitor for the iPhone.

One interesting product in development is the Nymi wristband. It looks like a typical fitness band, but instead of tallying steps it detects your heartbeat to confirm your identity.

The twist is that it isn't using your cardiac rhythm to unlock one device. The Nymi is designed to act like a replacement for physical keys and passwords by wirelessly confirming your identity to your smartphone, computer, front door, vehicle and even stores. It can also recognize gestures, so you can unlock your home with a wave.

Similar technology will likely find its way directly into other devices, including smartphones. Fitness devices are already including heart rate monitors as part of their health tracking, so it's a small jump to using them for security.

Ear shape

Sensitive touchscreens can pick up much more than a finger tap or swipe. With the right software and phone, they can detect the shape of a human ear.

That's the idea behind the Ergo Android app by Descartes Biometrics. When an ear is pressed against the screen, the points where it makes contact with the glass are mapped out and compared to a stored ear print. If it matches, the user is authenticated. The app is adjustable and can require multiple scans for the highest levels of security, or just one for people who feel they have a low risk of losing their phones.

For now, it's limited to unlocking a phone, but in theory the ear could be used to identify people for any number of uses on the phone, such as making purchases in app stores or signing into services.

There are a couple of potential advantages to using ear prints over fingerprints. For one, the size of the ear means it can be scanned using existing technology. There's no need to pay for a dedicated fingerprint sensor. It is also possible to figure out an ear shape from an image, something that could benefit law enforcement working with surveillance photos or videos.

Fingerprints can also change over time as people work with their hands, get injured and age. Advocates for ear biometrics claim that ears don't change nearly much over the course of a lifetime (unless they happen to belong to an MMA fighter).

Walk

If you've ever listened to someone walking past in the office and immediately known who it was, or spotted a friend from a distance by the way they moved, you've already seen the power of gait recognition.

For 30 years, researchers have tinkered with gait-recognition technology using high-resolution videos and specialized floors that sense pressure. The recent boom in inexpensive motion sensors like accelerometers and gyros have given new life to the field.

A wearable fitness device or smartphone moves along with your body when you walk. Many are already counting steps and speed. With the right software and sensors, they should be able to analyze a person's walk and determine if they are the rightful owner of those devices.

The benefit of gait recognition is that it can gather the necessary information in the background while people go about their normal routines. There's no need for the subject to touch their device or look into a camera.

Typing speed

Typing, like walking, varies from person to person. Keystroke biometrics record how a person types and calculates their unique pattern, speed and rhythm. It determines how long they hold down each key and the space of time between different letters.

Online learning site Coursera offers "Signature track" to students who want to get verified certificates for the courses they've taken. When classes are online, anyone could be playing the role of student. So Coursera set up a profile that requires a student to type in a sample phrase. When they need to prove their identity, say when turning in homework, they retype the phrase.

Keystrokes could be used to authenticate anyone working on a computer, so the system could appeal to companies that are watching out for unauthorized users on their internal systems.

Face recognition

Like fingerprints, face recognition is already being used in popular technology. Law enforcement and other entities are building databases to take advantage of recent advancements in facial recognition.

For facial recognition to succeed, devices need a clear, sharp image to work with. The cameras in smartphones and tablets have improved drastically and are on par with what you'll find in many point-and-shoot cameras. The software looks for patterns on the human face, such as distance between eyes, to identify people.

Samsung is one company that has taken advantage of improved camera technology and it now has a face-recognition unlock feature on its Galaxy smartphones. The feature is more of a novelty for now, because factors like lighting and camera angle often give false negatives.

Security is great for consumers, but it's not the primary goal of most facial-recognition tools. Law enforcement is building facial recognition databases. Identifying one person using their trail of selfies left online and in surveillance footage from stores could be a huge business. Some stores already use facial recognition to build profiles on repeat customers and collect data about how they shop.

 

5 biometric alternatives to the password - CNN.com 2014-04-04 18-35-56

Nutrition Zone Makes Major Moves In Sports Nutrition

 

Trenton S. Ulicny has joined Nutrition Zone as President.

Press Release: Nutrition Zone – Thu, 3 Apr, 2014 12:13 PM EDT

SANTA ANA, Calif., April 3, 2014 /PRNewswire/ -- Based in Nutrition Zone's Orange County, CA office, Ulicny will lead and manage operations, sales and marketing across all retail activities, franchising efforts, wholesale distribution, and consumer goods.

"Trent's decision to both invest in, and join Nutrition Zone as President, is a testament to what Nutrition Zone has created thus far, as well as the immense opportunity moving forward.  Trent brings with him a proven skill set and enthusiasm, and he will no doubt drive a dynamic environment here at Nutrition Zone that embodies a strong sense of team, product and operational excellence," stated Joe Eckstrom, Founder & CEO of Nutrition Zone.

Trenton S. Ulicny is the Co-Founder of TY KU, a Premium Sake & Spirits company, which he led to acclaimed success. Ulicny has also served as President & CEO of Robert Comstock Clothing.

Nutrition Zone has announced a partnership with ConeHead Investments, Inc (CHI), to aggressively build Nutrition Zone's Franchise Operations in the USA, starting immediately.

"Nutrition Zone is focused on identifying the best partners and practices in the industry. CHI has 18+ years of experience and over $100 Million in annual sales with their work with Cold Stone Creamery, embodying the experience we were looking for to ensure Nutrition Zone becomes the Premier Sports Nutrition store in the US and worldwide," said Trenton S. Ulicny, Nutrition Zone President.

Nutrition Zone
We are in the business of changing lives.
Nutrition Zone was founded to serve, educate and empower the community by improving the quality of our client's lives.  From inception, Nutrition Zone's customer service and sincerity has been at the forefront of its growth.  This is realized through highly educated team members who share our goal of making a positive, meaningful impact in our communities.
Nutrition Zone provides premium service and premium products at extremely competitive prices.

 

Nutrition Zone Makes Major Moves In Sports Nutrition - Yahoo Finance Canada 2014-04-04 18-22-01

Statin Alternative: More efficient new drugs to lower Cholesterol

 

 

A new class of experimental medicines can dramatically lower cholesterol, raising hopes of a fresh option for people who can't tolerate or don't get enough help from Lipitor and other statin drugs that have been used for this for decades.

The first large studies of these drugs were presented Saturday at an American College of Cardiology conference in Washington, and more will follow on Sunday.

Several companies are developing these drugs, which are aimed at 70 million Americans and millions more worldwide who have high LDL or "bad" cholesterol, a major risk for heart disease.

Three studies of Amgen Inc.'s version of these drugs, called evolocumab (ev-oh-LOKE-you-mab), found it lowered LDL or "bad" cholesterol by 55 to 66 percent from baseline levels compared to others who took a fake drug, and by nearly that much when compared to Merck's Zetia, another cholesterol medication.

As impressive as that is, it's still just part of the picture. Doctors want evidence that the way these drugs lower cholesterol also will lead to fewer heart attacks and deaths, because that proof already exists for statins. New studies are underway to test this, but Amgen said it will seek approval for its drug this year based on cholesterol-lowering alone.

That was enough to win approval for statins and Zetia, but use of Zetia has declined since 2008, when research showed it failed to help prevent heart attacks even though it cut cholesterol. Hopes are high that the new Amgen drug and others like it will do better.

"I would be happy to see it approved" on the cholesterol results alone, said Dr. Hadley Wilson, a cardiologist at Carolinas HealthCare System. "We need additional agents other than statins" to help patients, he said.

Nearly all current cholesterol medicines - fibrates, niacin and top-selling statins - are decades old. Statins such as Lipitor, Zocor and Crestor curb cholesterol production. Zetia, which came out about a decade ago, helps block the absorption of cholesterol from the intestine.

The new drugs block PCSK9, a substance that interferes with the liver's ability to remove cholesterol from the blood.

They have big drawbacks, though. Statins are pills sold as generics for as little as a dime a day. The new drugs are proteins rather than chemicals, and those tend to be very expensive to make. They also must be given as shots every two weeks or once a month. People can give the shots to themselves with a pen-like device. The companies developing the new medicines have not said what they might cost.

"We were very, very pleased" about how well patients accepted the shots, and if they offer better results, especially for those with inherited conditions, "people will accept it," said Dr. Michael Koren of Jacksonville Center for Clinical Research in Florida, who helped lead two of the studies.

The three Amgen studies involved about 2,000 patients in all. Doctors tested the drug in people with high cholesterol not taking other medicines, as a long-term (one-year) treatment in people already taking various medications and in combination with statins and other drugs in people with an inherited cholesterol disorder.

In general, side-effect rates were about the same for evolocumab vs. placebo or Zetia. In some studies, muscle aches, nausea and a few other problems were a little higher with the experimental drug.

Overall safety "is very, very encouraging," said Dr. Scott Wasserman, Amgen's executive medical director.

Researchers also said:

-Alirocumab, a similar drug being developed by Sanofi SA and Regeneron Pharmaceuticals Inc., lowered LDL cholesterol by 47 percent vs. 16 percent for Zetia in a study of about 100 people not taking any other drugs for high cholesterol.

-Bococizumab, from Pfizer Inc., lowered LDL 45 percent to 67 percent, depending on dose, compared to placebo in 354 people with high cholesterol also taking a statin.

"There's great interest" in all of these drugs, but doctors will wait for evidence that they lower heart risks, said Dr. Neil Stone, a Northwestern University cardiologist and spokesman for the American Heart Association.

It may be easier to justify their use in patients with genes that cause high cholesterol at an early age, he said.

A spokeswoman for the federal Food and Drug Administration, Sandy Walsh, suggested that might be the case.

"Although we cannot comment on the likelihood of approval based solely on specific indications or populations," two drugs recently were approved based on cholesterol-lowering for people with inherited conditions.

A decision on approval also will be influenced by how much the drug lowers cholesterol, its effects on other fats in the blood and other heart signs such as inflammation and blood pressure, and its safety.

 

A Better Prostate Cancer Test Is Here 2014-04-02 11-42-38